Hepatosplenomegaly. Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Hepatosplenomegaly (HPM) is a condition that affects the liver and the spleen. The condition can be mild, moderate, or severe. It can also be a symptom of more serious medical conditions, including cancer. Mild cases of HPM can be treated with minimal intervention.
Also Know, what causes liver and spleen enlargement? An enlarged spleen can be caused by infections, cirrhosis and other liver diseases, blood diseases characterized by abnormal blood cells, problems with the lymph system, or other conditions. Other causes of an enlarged spleen include: Inflammatory diseases such as sarcoidosis, lupus, and rheumatoid arthritis.
Just so, how is Hepatosplenomegaly treated?
When the underlying cause is cancer, you need suitable treatments that may include chemotherapy, radiotherapy, and surgery to remove the tumor. Liver transplant. If your case is severe, such as being in the final stages of cirrhosis, you may require a liver transplant.
Is Hepatosplenomegaly reversible?
Liver synthetic function is usually normal. All these abnormalities, including the hepatomegaly, are readily reversible with sustained euglycemic control. The other major cause of hepatomegaly in patients with diabetes is steatosis.
How do you reduce hepatomegaly?
To reduce your risk of liver disease, you can: Eat a healthy diet. Drink alcohol in moderation, if at all. Follow directions when taking medications, vitamins or supplements. Limit contact with chemicals. Maintain a healthy weight. Quit smoking. Use supplements with caution.
What can cause Hepatosplenomegaly?
Common causes Infection: Acute viral hepatitis. Infectious mononucleosis. Hematologic diseases: Myeloproliferative disease. Leukaemia. Metabolic disease: Niemann-Pick disease. Chronic liver disease and portal hypertension: Chronic active hepatitis. Amyloidosis. Acromegaly. Systemic lupus erythematosus. Sarcoidosis.
What is a Hepatosplenomegaly in medical terms?
Medical Definition of Hepatosplenomegaly Hepatosplenomegaly: Abnormal enlargement of the liver and spleen. Hepatosplenomegaly is typically associated with chronic liver diseases.
Can an enlarged spleen go back to normal size?
Depending upon the cause, the enlarged spleen may return to normal size and function when the underlying disease is treated or resolved. Commonly, in infectious mononucleosis, the spleen returns to normal as the infection gets better.
Is enlarged liver and spleen dangerous?
Serious or life-threatening causes of enlarged liver and spleen. In some cases, enlarged liver and spleen may be a symptom of a serious or life-threatening condition that should be immediately evaluated by a health care provider. These include: Acute hepatitis (liver inflammation)
Can you live without a spleen?
You can live without a spleen. But because the spleen plays a crucial role in the body’s ability to fight off bacteria, living without the organ makes you more likely to develop infections, especially dangerous ones such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae.
What size of liver is dangerous?
A liver span 2 to 3 cm larger or smaller than these values is considered abnormal.
What is the normal size of a liver?
The size of the liver increases with age, from an average span of 5 cm at the age of five years, to 15 cm in adulthood . The size of the normal liver also varies with sex and body size [2-4]. The normal liver weighs 1.4 to 1.5 kg in men and 1.2 to 1.4 kg in women .
Why does liver size increase?
Enlarged liver is usually caused by liver disorders related to excessive alcohol use, congestive heart failure, glycogen storage disease, viral hepatitis, liver cancer, cirrhosis, and steatosis (fat in the liver).
Does enlarged liver cause pain?
Enlarged Liver. An enlarged liver is swollen beyond its normal size. Possible causes include cancer and excessive alcohol consumption. Symptoms, when they appear, include jaundice (yellowing of the skin) and pain in the upper abdomen.
Where is my liver and spleen?
Your spleen is an organ located just below your left rib cage. Many conditions — including infections, liver disease and some cancers — can cause an enlarged spleen, also known as splenomegaly (spleh-no-MEG-uh-lee).
How do you know if your spleen is swollen?
Symptoms you may experience with an enlarged spleen include: pressure or pain in the left upper part of your abdomen (near the stomach), feeling full without eating a large meal, or pain your left shoulder blade or shoulder area when taking a deep breath.
Does fatty liver cause enlarged liver?
Nonalcoholic fatty liver disease. Compared with a normal liver (left), a fatty liver (right) appears enlarged and discolored. Tissue samples reveal fat deposits in nonalcoholic fatty liver disease, while inflammation and advanced scarring (cirrhosis) are visible in nonalcoholic steatohepatitis.